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Excess NO production and associated cellular desensitization, along with vascular inflammation and structural changes, also contribute to the complex vasculature-related pathology of MS [276, 277]

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The number of self-reported illnesses was similar between groups after 90 days of aged garlic extract or placebo supplementation, but aged garlic extract significantly reduced the severity of self-reported cold or flu symptoms (87)

Significant progress in MNM research has addressed TME-related challenges, leading to improved treatment outcomes